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Protein diaphanous homolog 1 (Diaph1) promotes myofibroblastic activation of hepatic stellate cells by regulating Rab5a activity and TGFβ receptor endocytosis

TGFβ induces the differentiation of hepatic stellate cells (HSCs) into tumor-promoting myofibroblasts but underlying mechanisms remain incompletely understood. Because endocytosis of TGFβ receptor II (TβRII), in response to TGFβ stimulation, is a prerequisite for TGF signaling, we investigated the r...

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Detalles Bibliográficos
Autores principales:	Liu, Donglian, Fu, Xinhui, Wang, Yuanguo, Wang, Xianghu, Wang, Hua, Wen, Jialing, Kang, Ningling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686927/ https://www.ncbi.nlm.nih.gov/pubmed/32304339 http://dx.doi.org/10.1096/fj.201903033R

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