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Modeling the effect of delay strategy on transmission dynamics of HIV/AIDS disease
In this manuscript, we investigate a nonlinear delayed model to study the dynamics of human-immunodeficiency-virus in the population. For analysis, we find the equilibria of a susceptible–infectious–immune system with a delay term. The well-established tools such as the Routh–Hurwitz criterion, Volt...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686949/ https://www.ncbi.nlm.nih.gov/pubmed/33250928 http://dx.doi.org/10.1186/s13662-020-03116-8 |
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author | Raza, Ali Ahmadian, Ali Rafiq, Muhammad Salahshour, Soheil Naveed, Muhammad Ferrara, Massimiliano Soori, Atif Hassan |
author_facet | Raza, Ali Ahmadian, Ali Rafiq, Muhammad Salahshour, Soheil Naveed, Muhammad Ferrara, Massimiliano Soori, Atif Hassan |
author_sort | Raza, Ali |
collection | PubMed |
description | In this manuscript, we investigate a nonlinear delayed model to study the dynamics of human-immunodeficiency-virus in the population. For analysis, we find the equilibria of a susceptible–infectious–immune system with a delay term. The well-established tools such as the Routh–Hurwitz criterion, Volterra–Lyapunov function, and Lasalle invariance principle are presented to investigate the stability of the model. The reproduction number and sensitivity of parameters are investigated. If the delay tactics are decreased, then the disease is endemic. On the other hand, if the delay tactics are increased then the disease is controlled in the population. The effect of the delay tactics with subpopulations is investigated. More precisely, all parameters are dependent on delay terms. In the end, to give the strength to a theoretical analysis of the model, a computer simulation is presented. |
format | Online Article Text |
id | pubmed-7686949 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-76869492020-11-25 Modeling the effect of delay strategy on transmission dynamics of HIV/AIDS disease Raza, Ali Ahmadian, Ali Rafiq, Muhammad Salahshour, Soheil Naveed, Muhammad Ferrara, Massimiliano Soori, Atif Hassan Adv Differ Equ Research In this manuscript, we investigate a nonlinear delayed model to study the dynamics of human-immunodeficiency-virus in the population. For analysis, we find the equilibria of a susceptible–infectious–immune system with a delay term. The well-established tools such as the Routh–Hurwitz criterion, Volterra–Lyapunov function, and Lasalle invariance principle are presented to investigate the stability of the model. The reproduction number and sensitivity of parameters are investigated. If the delay tactics are decreased, then the disease is endemic. On the other hand, if the delay tactics are increased then the disease is controlled in the population. The effect of the delay tactics with subpopulations is investigated. More precisely, all parameters are dependent on delay terms. In the end, to give the strength to a theoretical analysis of the model, a computer simulation is presented. Springer International Publishing 2020-11-25 2020 /pmc/articles/PMC7686949/ /pubmed/33250928 http://dx.doi.org/10.1186/s13662-020-03116-8 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Raza, Ali Ahmadian, Ali Rafiq, Muhammad Salahshour, Soheil Naveed, Muhammad Ferrara, Massimiliano Soori, Atif Hassan Modeling the effect of delay strategy on transmission dynamics of HIV/AIDS disease |
title | Modeling the effect of delay strategy on transmission dynamics of HIV/AIDS disease |
title_full | Modeling the effect of delay strategy on transmission dynamics of HIV/AIDS disease |
title_fullStr | Modeling the effect of delay strategy on transmission dynamics of HIV/AIDS disease |
title_full_unstemmed | Modeling the effect of delay strategy on transmission dynamics of HIV/AIDS disease |
title_short | Modeling the effect of delay strategy on transmission dynamics of HIV/AIDS disease |
title_sort | modeling the effect of delay strategy on transmission dynamics of hiv/aids disease |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686949/ https://www.ncbi.nlm.nih.gov/pubmed/33250928 http://dx.doi.org/10.1186/s13662-020-03116-8 |
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