Celastrol attenuates arterial and valvular calcification via inhibiting BMP2/Smad1/5 signalling

Vascular calcification is an important risk factor for the mortality and morbidity in chronic kidney disease (CKD). Unfortunately, until now there is no certain medication targeting vascular calcification in CKD. In this study, we explored the inhibitory effect of celastrol on high calcium–induced v...

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Detalles Bibliográficos
Autores principales: Su, Zhongping, Zong, Pengyu, Chen, Ji, Yang, Shuo, Shen, Yihui, Lu, Yan, Yang, Chuanxi, Kong, Xiangqing, Sheng, Yanhui, Sun, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686965/
https://www.ncbi.nlm.nih.gov/pubmed/32954678
http://dx.doi.org/10.1111/jcmm.15779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686965/
https://www.ncbi.nlm.nih.gov/pubmed/32954678
http://dx.doi.org/10.1111/jcmm.15779

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