miR‐30b Promotes spinal cord sensory function recovery via the Sema3A/NRP‐1/PlexinA1/RhoA/ROCK Pathway

Spinal cord injury (SCI) induces both motor and sensory dysfunctions. We wondered whether miR‐30b could promote primary sensory neuron (PSN) axon growth in inhibitory microenvironment. The neurite growth was promoted by miR‐30b agomir and inhibited by antagomir. MiR‐30b targeted and degraded sema3A...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Li, Bo, Wang, Zhijie, Wang, Fengyan, Liang, Jing, Chen, Chuanjie, Zhao, Lei, Zhou, Bo, Guo, Xiaoling, Ren, Liqun, Yuan, Xin, Chen, Xueming, Wang, Tianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686968/
https://www.ncbi.nlm.nih.gov/pubmed/32977360
http://dx.doi.org/10.1111/jcmm.15591

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