Cargando…
Recent advances on the roles of LncRNAs in cardiovascular disease
Cardiovascular diseases are a main cause of mortality whose prevalence continues to increase worldwide. Long non‐coding RNAs (lncRNAs) regulate a variety of biological processes by modifying and regulating transcription of coding genes, directly binding to proteins and even coding proteins themselve...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686979/ https://www.ncbi.nlm.nih.gov/pubmed/32969576 http://dx.doi.org/10.1111/jcmm.15880 |
_version_ | 1783613436607856640 |
---|---|
author | Fang, Yexian Xu, Yuerong Wang, Runze Hu, Lang Guo, Dong Xue, Feng Guo, Wangang Zhang, Dongwei Hu, Jianqiang Li, Yan Zhang, Wei Zhang, Mingming |
author_facet | Fang, Yexian Xu, Yuerong Wang, Runze Hu, Lang Guo, Dong Xue, Feng Guo, Wangang Zhang, Dongwei Hu, Jianqiang Li, Yan Zhang, Wei Zhang, Mingming |
author_sort | Fang, Yexian |
collection | PubMed |
description | Cardiovascular diseases are a main cause of mortality whose prevalence continues to increase worldwide. Long non‐coding RNAs (lncRNAs) regulate a variety of biological processes by modifying and regulating transcription of coding genes, directly binding to proteins and even coding proteins themselves. LncRNAs play key roles in the occurrence and development of myocardial infarction, heart failure, myocardial hypertrophy, arrhythmias and other pathological processes that significantly affect the prognosis and survival of patients with cardiovascular diseases. We here review the latest research on lncRNAs in cardiovascular diseases as a basis to formulate future research on prevention and treatment of cardiovascular diseases. |
format | Online Article Text |
id | pubmed-7686979 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76869792020-12-03 Recent advances on the roles of LncRNAs in cardiovascular disease Fang, Yexian Xu, Yuerong Wang, Runze Hu, Lang Guo, Dong Xue, Feng Guo, Wangang Zhang, Dongwei Hu, Jianqiang Li, Yan Zhang, Wei Zhang, Mingming J Cell Mol Med Reviews Cardiovascular diseases are a main cause of mortality whose prevalence continues to increase worldwide. Long non‐coding RNAs (lncRNAs) regulate a variety of biological processes by modifying and regulating transcription of coding genes, directly binding to proteins and even coding proteins themselves. LncRNAs play key roles in the occurrence and development of myocardial infarction, heart failure, myocardial hypertrophy, arrhythmias and other pathological processes that significantly affect the prognosis and survival of patients with cardiovascular diseases. We here review the latest research on lncRNAs in cardiovascular diseases as a basis to formulate future research on prevention and treatment of cardiovascular diseases. John Wiley and Sons Inc. 2020-09-24 2020-11 /pmc/articles/PMC7686979/ /pubmed/32969576 http://dx.doi.org/10.1111/jcmm.15880 Text en © 2020 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Fang, Yexian Xu, Yuerong Wang, Runze Hu, Lang Guo, Dong Xue, Feng Guo, Wangang Zhang, Dongwei Hu, Jianqiang Li, Yan Zhang, Wei Zhang, Mingming Recent advances on the roles of LncRNAs in cardiovascular disease |
title | Recent advances on the roles of LncRNAs in cardiovascular disease |
title_full | Recent advances on the roles of LncRNAs in cardiovascular disease |
title_fullStr | Recent advances on the roles of LncRNAs in cardiovascular disease |
title_full_unstemmed | Recent advances on the roles of LncRNAs in cardiovascular disease |
title_short | Recent advances on the roles of LncRNAs in cardiovascular disease |
title_sort | recent advances on the roles of lncrnas in cardiovascular disease |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686979/ https://www.ncbi.nlm.nih.gov/pubmed/32969576 http://dx.doi.org/10.1111/jcmm.15880 |
work_keys_str_mv | AT fangyexian recentadvancesontherolesoflncrnasincardiovasculardisease AT xuyuerong recentadvancesontherolesoflncrnasincardiovasculardisease AT wangrunze recentadvancesontherolesoflncrnasincardiovasculardisease AT hulang recentadvancesontherolesoflncrnasincardiovasculardisease AT guodong recentadvancesontherolesoflncrnasincardiovasculardisease AT xuefeng recentadvancesontherolesoflncrnasincardiovasculardisease AT guowangang recentadvancesontherolesoflncrnasincardiovasculardisease AT zhangdongwei recentadvancesontherolesoflncrnasincardiovasculardisease AT hujianqiang recentadvancesontherolesoflncrnasincardiovasculardisease AT liyan recentadvancesontherolesoflncrnasincardiovasculardisease AT zhangwei recentadvancesontherolesoflncrnasincardiovasculardisease AT zhangmingming recentadvancesontherolesoflncrnasincardiovasculardisease |