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Recent advances on the roles of LncRNAs in cardiovascular disease

Cardiovascular diseases are a main cause of mortality whose prevalence continues to increase worldwide. Long non‐coding RNAs (lncRNAs) regulate a variety of biological processes by modifying and regulating transcription of coding genes, directly binding to proteins and even coding proteins themselve...

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Autores principales: Fang, Yexian, Xu, Yuerong, Wang, Runze, Hu, Lang, Guo, Dong, Xue, Feng, Guo, Wangang, Zhang, Dongwei, Hu, Jianqiang, Li, Yan, Zhang, Wei, Zhang, Mingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686979/
https://www.ncbi.nlm.nih.gov/pubmed/32969576
http://dx.doi.org/10.1111/jcmm.15880
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author Fang, Yexian
Xu, Yuerong
Wang, Runze
Hu, Lang
Guo, Dong
Xue, Feng
Guo, Wangang
Zhang, Dongwei
Hu, Jianqiang
Li, Yan
Zhang, Wei
Zhang, Mingming
author_facet Fang, Yexian
Xu, Yuerong
Wang, Runze
Hu, Lang
Guo, Dong
Xue, Feng
Guo, Wangang
Zhang, Dongwei
Hu, Jianqiang
Li, Yan
Zhang, Wei
Zhang, Mingming
author_sort Fang, Yexian
collection PubMed
description Cardiovascular diseases are a main cause of mortality whose prevalence continues to increase worldwide. Long non‐coding RNAs (lncRNAs) regulate a variety of biological processes by modifying and regulating transcription of coding genes, directly binding to proteins and even coding proteins themselves. LncRNAs play key roles in the occurrence and development of myocardial infarction, heart failure, myocardial hypertrophy, arrhythmias and other pathological processes that significantly affect the prognosis and survival of patients with cardiovascular diseases. We here review the latest research on lncRNAs in cardiovascular diseases as a basis to formulate future research on prevention and treatment of cardiovascular diseases.
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spelling pubmed-76869792020-12-03 Recent advances on the roles of LncRNAs in cardiovascular disease Fang, Yexian Xu, Yuerong Wang, Runze Hu, Lang Guo, Dong Xue, Feng Guo, Wangang Zhang, Dongwei Hu, Jianqiang Li, Yan Zhang, Wei Zhang, Mingming J Cell Mol Med Reviews Cardiovascular diseases are a main cause of mortality whose prevalence continues to increase worldwide. Long non‐coding RNAs (lncRNAs) regulate a variety of biological processes by modifying and regulating transcription of coding genes, directly binding to proteins and even coding proteins themselves. LncRNAs play key roles in the occurrence and development of myocardial infarction, heart failure, myocardial hypertrophy, arrhythmias and other pathological processes that significantly affect the prognosis and survival of patients with cardiovascular diseases. We here review the latest research on lncRNAs in cardiovascular diseases as a basis to formulate future research on prevention and treatment of cardiovascular diseases. John Wiley and Sons Inc. 2020-09-24 2020-11 /pmc/articles/PMC7686979/ /pubmed/32969576 http://dx.doi.org/10.1111/jcmm.15880 Text en © 2020 The Authors. Journal of Cellular and Molecular Medicine published by Foundation for Cellular and Molecular Medicine and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Fang, Yexian
Xu, Yuerong
Wang, Runze
Hu, Lang
Guo, Dong
Xue, Feng
Guo, Wangang
Zhang, Dongwei
Hu, Jianqiang
Li, Yan
Zhang, Wei
Zhang, Mingming
Recent advances on the roles of LncRNAs in cardiovascular disease
title Recent advances on the roles of LncRNAs in cardiovascular disease
title_full Recent advances on the roles of LncRNAs in cardiovascular disease
title_fullStr Recent advances on the roles of LncRNAs in cardiovascular disease
title_full_unstemmed Recent advances on the roles of LncRNAs in cardiovascular disease
title_short Recent advances on the roles of LncRNAs in cardiovascular disease
title_sort recent advances on the roles of lncrnas in cardiovascular disease
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7686979/
https://www.ncbi.nlm.nih.gov/pubmed/32969576
http://dx.doi.org/10.1111/jcmm.15880
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