Cargando…

Fibroblast growth factor 1 ameliorates adipose tissue inflammation and systemic insulin resistance via enhancing adipocyte mTORC2/Rictor signal

Obesity‐induced activation and proliferation of resident macrophages and infiltration of circulating monocytes in adipose tissues contribute to adipose tissue inflammation and insulin resistance. These effects further promote the development of metabolic syndromes, such as type 2 diabetes, which is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Longwei, Fan, Miaojuan, Zhao, Lijun, Yun, Hongyan, Yang, Yan, Wang, Chen, Qin, Di
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687011/ https://www.ncbi.nlm.nih.gov/pubmed/32979037 http://dx.doi.org/10.1111/jcmm.15872

Ejemplares similares

Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors
por: Lee, Dongjun, et al.
Publicado: (2014)

mTORC2/Akt activation in adipocytes is required for adipose tissue inflammation in tuberculosis
por: Martinez, Nuria, et al.
Publicado: (2019)

Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis()()
por: Schmidt, Katharina M., et al.
Publicado: (2018)

Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis
por: Li, Jianzhong, et al.
Publicado: (2015)

Rictor/mTORC2 facilitates central regulation of energy and glucose homeostasis
por: Kocalis, Heidi E., et al.
Publicado: (2014)

microRNA-153 Targets mTORC2 Component Rictor to Inhibit Glioma Cells
por: Cui, Yan, et al.
Publicado: (2016)

Involvement of Rictor/mTORC2 in cardiomyocyte differentiation of mouse embryonic stem cells in vitro
por: Zheng, Bei, et al.
Publicado: (2017)

Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan
por: Lamming, Dudley W, et al.
Publicado: (2014)

The mTORC2 Component Rictor Contributes to Cisplatin Resistance in Human Ovarian Cancer Cells
por: Im-aram, Akechai, et al.
Publicado: (2013)

Inhibition of mTORC2 component RICTOR impairs tumor growth in pancreatic cancer models
por: Schmidt, Katharina M., et al.
Publicado: (2017)

TELO2 induced progression of colorectal cancer by binding with RICTOR through mTORC2
por: Guo, Zheng, et al.
Publicado: (2021)

Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology
por: Thomanetz, Venus, et al.
Publicado: (2013)

Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma
por: Benavides-Serrato, Angelica, et al.
Publicado: (2017)

PTH(1-34) activates the migration and adhesion of BMSCs through the rictor/mTORC2 pathway
por: Lv, Zhong, et al.
Publicado: (2020)

RICTOR/mTORC2 affects tumorigenesis and therapeutic efficacy of mTOR inhibitors in esophageal squamous cell carcinoma
por: Lu, Zhaoming, et al.
Publicado: (2020)

Rictor/mTORC2 Is Essential for Maintaining a Balance Between β-Cell Proliferation and Cell Size
por: Gu, Yanyun, et al.
Publicado: (2011)

Correction: Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma
por: Benavides-Serrato, Angelica, et al.
Publicado: (2019)

The mTORC2 Component Rictor Is Required for Load‐Induced Bone Formation in Late‐Stage Skeletal Cells
por: Lewis, Karl J, et al.
Publicado: (2020)

Retraction: Specific blockade of Rictor-mTOR association inhibits mTORC2 activity and is cytotoxic in glioblastoma
Publicado: (2023)

The Deubiquitinase USP39 Promotes ESCC Tumorigenesis Through Pre-mRNA Splicing of the mTORC2 Component Rictor
por: Zhao, Yuan, et al.
Publicado: (2021)

Regulation of adiposity by mTORC1
por: Magdalon, Juliana, et al.
Publicado: (2017)

Mdm20 Modulates Actin Remodeling through the mTORC2 Pathway via Its Effect on Rictor Expression
por: Yasuda, Kunihiko, et al.
Publicado: (2015)

Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma
por: Akgül, Seçkin, et al.
Publicado: (2018)

Rictor/mTORC2 involves mitochondrial function in ES cells derived cardiomyocytes via mitochondrial Connexin 43
por: Wang, Jia-dan, et al.
Publicado: (2021)

Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss
por: Fu, Xiaolong, et al.
Publicado: (2022)

mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells
por: Chu, Qun, et al.
Publicado: (2022)

PTEN negatively regulates mTORC2 formation and signaling in grade IV glioma via Rictor hyperphosphorylation at Thr1135 and direct the mode of action of an mTORC1/2 inhibitor
por: Bhattacharya, K, et al.
Publicado: (2016)

Correction to: mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells
por: Chu, Qun, et al.
Publicado: (2022)

Rapamycin Ameliorates Inflammation and Fibrosis in the Early Phase of Cirrhotic Portal Hypertension in Rats through Inhibition of mTORC1 but Not mTORC2
por: Wang, Weijie, et al.
Publicado: (2014)

mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia
por: Paolella, Lauren M., et al.
Publicado: (2019)

mTORC2 helps brown adipose tissue fuel up
por: Short, Ben
Publicado: (2014)

Inhibition of the mTORC1 pathway alleviates adipose tissue fibrosis
por: Gong, Sa, et al.
Publicado: (2023)

Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition
por: Ruicci, Kara M., et al.
Publicado: (2019)

Asparagine reinforces mTORC1 signaling to boost thermogenesis and glycolysis in adipose tissues
por: Xu, Yingjiang, et al.
Publicado: (2021)

Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2
por: Humphrey, Sean J., et al.
Publicado: (2013)

mTORC2/AKT/HSF1/HuR constitute a feed-forward loop regulating Rictor expression and tumor growth in glioblastoma
por: Holmes, Brent, et al.
Publicado: (2017)

Erratum to: Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition
por: Ruicci, Kara M., et al.
Publicado: (2019)

Correction for Fu et al., Activation of Rictor/mTORC2 signaling acts as a pivotal strategy to protect against sensorineural hearing loss
Publicado: (2022)

mTORC1 and mTORC2 in cancer and the tumor microenvironment
por: Kim, Laura C., et al.
Publicado: (2016)

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension
por: Tang, Haiyang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_li43rr8og9o126gfpo8gvnkrjn