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Survey on screening for paediatric non‐alcoholic fatty liver disease in clinical practice in Dutch hospitals

AIM: Non‐alcoholic fatty liver disease (NAFLD) is a highly prevalent liver disease that affects 34% of children with obesity. Besides the liver‐related morbidity, NAFLD also increases the risk of cardiometabolic diseases at adult age. Diverse screening recommendations exist on paediatric NAFLD. The...

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Autores principales: Draijer, Laura G., Haggenburg, Sabine, Benninga, Marc A., Chegary, Malika, Koot, Bart G. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687083/
https://www.ncbi.nlm.nih.gov/pubmed/32271954
http://dx.doi.org/10.1111/apa.15294
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author Draijer, Laura G.
Haggenburg, Sabine
Benninga, Marc A.
Chegary, Malika
Koot, Bart G. P.
author_facet Draijer, Laura G.
Haggenburg, Sabine
Benninga, Marc A.
Chegary, Malika
Koot, Bart G. P.
author_sort Draijer, Laura G.
collection PubMed
description AIM: Non‐alcoholic fatty liver disease (NAFLD) is a highly prevalent liver disease that affects 34% of children with obesity. Besides the liver‐related morbidity, NAFLD also increases the risk of cardiometabolic diseases at adult age. Diverse screening recommendations exist on paediatric NAFLD. The aim of this study was to assess screening practices among paediatricians managing children with obesity in the Netherlands. METHODS: Between 2016 and 2017, an Internet‐based survey was sent to all 167 members of the endocrinology section of the Dutch Paediatricians Society, that includes all paediatricians involved in obesity care. Descriptive statistics (frequencies) were used to analyse responses. RESULTS: In total, 42/167 (25%) of the invited paediatricians responded. Thirty‐six of 42 respondents (86%) screen for NAFLD. One‐third of those do not follow any guideline. Most respondents use ALT as screening tool, with thresholds varying between 21‐80 IU/L. The majority (29/36) indicate they lack guidance on screening and follow‐up. CONCLUSION: In this study sample of Dutch paediatricians, screening for paediatric NAFLD is widely, albeit not universally, performed and in a highly variable way. This underlines the need come to a uniform and comprehensive screening strategy and raise awareness about NAFLD among physicians treating children with obesity.
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spelling pubmed-76870832020-12-03 Survey on screening for paediatric non‐alcoholic fatty liver disease in clinical practice in Dutch hospitals Draijer, Laura G. Haggenburg, Sabine Benninga, Marc A. Chegary, Malika Koot, Bart G. P. Acta Paediatr Regular Articles and Brief Reports AIM: Non‐alcoholic fatty liver disease (NAFLD) is a highly prevalent liver disease that affects 34% of children with obesity. Besides the liver‐related morbidity, NAFLD also increases the risk of cardiometabolic diseases at adult age. Diverse screening recommendations exist on paediatric NAFLD. The aim of this study was to assess screening practices among paediatricians managing children with obesity in the Netherlands. METHODS: Between 2016 and 2017, an Internet‐based survey was sent to all 167 members of the endocrinology section of the Dutch Paediatricians Society, that includes all paediatricians involved in obesity care. Descriptive statistics (frequencies) were used to analyse responses. RESULTS: In total, 42/167 (25%) of the invited paediatricians responded. Thirty‐six of 42 respondents (86%) screen for NAFLD. One‐third of those do not follow any guideline. Most respondents use ALT as screening tool, with thresholds varying between 21‐80 IU/L. The majority (29/36) indicate they lack guidance on screening and follow‐up. CONCLUSION: In this study sample of Dutch paediatricians, screening for paediatric NAFLD is widely, albeit not universally, performed and in a highly variable way. This underlines the need come to a uniform and comprehensive screening strategy and raise awareness about NAFLD among physicians treating children with obesity. John Wiley and Sons Inc. 2020-04-20 2020-11 /pmc/articles/PMC7687083/ /pubmed/32271954 http://dx.doi.org/10.1111/apa.15294 Text en © 2020 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Regular Articles and Brief Reports
Draijer, Laura G.
Haggenburg, Sabine
Benninga, Marc A.
Chegary, Malika
Koot, Bart G. P.
Survey on screening for paediatric non‐alcoholic fatty liver disease in clinical practice in Dutch hospitals
title Survey on screening for paediatric non‐alcoholic fatty liver disease in clinical practice in Dutch hospitals
title_full Survey on screening for paediatric non‐alcoholic fatty liver disease in clinical practice in Dutch hospitals
title_fullStr Survey on screening for paediatric non‐alcoholic fatty liver disease in clinical practice in Dutch hospitals
title_full_unstemmed Survey on screening for paediatric non‐alcoholic fatty liver disease in clinical practice in Dutch hospitals
title_short Survey on screening for paediatric non‐alcoholic fatty liver disease in clinical practice in Dutch hospitals
title_sort survey on screening for paediatric non‐alcoholic fatty liver disease in clinical practice in dutch hospitals
topic Regular Articles and Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687083/
https://www.ncbi.nlm.nih.gov/pubmed/32271954
http://dx.doi.org/10.1111/apa.15294
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