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Tnfaip3 expression in pulmonary conventional type 1 Langerin‐expressing dendritic cells regulates T helper 2‐mediated airway inflammation in mice

BACKGROUND: Conventional type 1 dendritic cells (cDC1s) control anti‐viral and anti‐tumor immunity by inducing antigen‐specific cytotoxic CD8(+) T‐cell responses. Controversy exists whether cDC1s also control CD4(+) T helper 2 (Th2) cell responses, since suppressive and activating roles have been re...

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Detalles Bibliográficos
Autores principales: Vroman, Heleen, van Uden, Denise, Bergen, Ingrid M., van Hulst, Jennifer A. C., Lukkes, Melanie, van Loo, Geert, Clausen, Björn E., Boon, Louis, Lambrecht, Bart N., Hammad, Hamida, Hendriks, Rudi W., Kool, Mirjam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687104/
https://www.ncbi.nlm.nih.gov/pubmed/32329078
http://dx.doi.org/10.1111/all.14334