Mucosal concentrations of N‐acetyl‐5‐aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine

BACKGROUND AND AIM: 5‐Aminosalicylic acid (5‐ASA) is a fundamental treatment for mild‐to‐moderate ulcerative colitis (UC). 5‐ASA is taken up into the colonic mucosa and metabolized to N‐acetyl‐5‐ASA (Ac‐5‐ASA). Few studies have assessed whether mucosal 5‐ASA and Ac‐5‐ASA concentrations are associate...

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Detalles Bibliográficos
Autores principales: Fukuda, Tomohiro, Naganuma, Makoto, Takabayashi, Kaoru, Hagihara, Yuya, Tanemoto, Shun, Nomura, Ena, Yoshimatsu, Yusuke, Sugimoto, Shinya, Nanki, Kosaku, Mizuno, Shinta, Mikami, Yohei, Fukuhara, Kayoko, Sujino, Tomohisa, Mutaguchi, Makoto, Inoue, Nagamu, Ogata, Haruhiko, Iwao, Yasushi, Abe, Takayuki, Kanai, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Clinical Gastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687243/
https://www.ncbi.nlm.nih.gov/pubmed/32250471
http://dx.doi.org/10.1111/jgh.15059

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