Cargando…

Embryo‐derived teratoma in vitro biological system reveals antitumor and embryotoxic activity of valproate

Antiepileptic/teratogen valproate (VPA) is a histone deacetylase inhibitor/epigenetic drug proposed for the antitumor therapy where it is generally crucial to target poorly or undifferentiated cells to prevent a recurrence. Transplanted rodent gastrulating embryos‐proper (primitive streak and three...

Descripción completa

Detalles Bibliográficos
Autores principales: Plazibat, Milvija, Katušić Bojanac, Ana, Himerleich Perić, Marta, Gamulin, Ozren, Rašić, Mario, Radonić, Vedran, Škrabić, Marko, Krajačić, Maria, Krasić, Jure, Sinčić, Nino, Jurić‐Lekić, Gordana, Balarin, Maja, Bulić‐Jakuš, Floriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687280/
https://www.ncbi.nlm.nih.gov/pubmed/32056377
http://dx.doi.org/10.1111/febs.15248