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Guillain-Barré syndrome associated with COVID-19 infection

We are reporting a case of Acute Post-Infectious Flaccid paralysis also commonly known as Guillain-Barré Syndrome (GBS) in a patient with confirmed COVID-19 infection. GBS often occurs following an infectious trigger which induces autoimmune reaction causing damage to peripheral nerves. So far, only...

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Autores principales: Manji, Hussein Karim, George, Upendo, Mkopi, Namala Patrick, Manji, Karim Premji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687474/
https://www.ncbi.nlm.nih.gov/pubmed/33282073
http://dx.doi.org/10.11604/pamj.supp.2020.35.2.25003
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author Manji, Hussein Karim
George, Upendo
Mkopi, Namala Patrick
Manji, Karim Premji
author_facet Manji, Hussein Karim
George, Upendo
Mkopi, Namala Patrick
Manji, Karim Premji
author_sort Manji, Hussein Karim
collection PubMed
description We are reporting a case of Acute Post-Infectious Flaccid paralysis also commonly known as Guillain-Barré Syndrome (GBS) in a patient with confirmed COVID-19 infection. GBS often occurs following an infectious trigger which induces autoimmune reaction causing damage to peripheral nerves. So far, only 8 cases have been described in association with COVID-19. This is the first to be described in Tanzania in an African Child, and probably the first in the continent. This report is presented for clinicians to be aware and for the medical fraternity to look into this unusual presentation which may shed some more light on possible pathways of the pathogenesis and clinical manifestations. We recommend that the presentation of GBS with acute respiratory distress should warrant extra precaution and a testing for COVID-19 especially when the symptoms of COVID-19 are protean.
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spelling pubmed-76874742020-12-03 Guillain-Barré syndrome associated with COVID-19 infection Manji, Hussein Karim George, Upendo Mkopi, Namala Patrick Manji, Karim Premji Pan Afr Med J Case Report We are reporting a case of Acute Post-Infectious Flaccid paralysis also commonly known as Guillain-Barré Syndrome (GBS) in a patient with confirmed COVID-19 infection. GBS often occurs following an infectious trigger which induces autoimmune reaction causing damage to peripheral nerves. So far, only 8 cases have been described in association with COVID-19. This is the first to be described in Tanzania in an African Child, and probably the first in the continent. This report is presented for clinicians to be aware and for the medical fraternity to look into this unusual presentation which may shed some more light on possible pathways of the pathogenesis and clinical manifestations. We recommend that the presentation of GBS with acute respiratory distress should warrant extra precaution and a testing for COVID-19 especially when the symptoms of COVID-19 are protean. The African Field Epidemiology Network 2020-07-18 /pmc/articles/PMC7687474/ /pubmed/33282073 http://dx.doi.org/10.11604/pamj.supp.2020.35.2.25003 Text en ©Hussein Karim Manji et al. https://creativecommons.org/licenses/by/4.0 Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Manji, Hussein Karim
George, Upendo
Mkopi, Namala Patrick
Manji, Karim Premji
Guillain-Barré syndrome associated with COVID-19 infection
title Guillain-Barré syndrome associated with COVID-19 infection
title_full Guillain-Barré syndrome associated with COVID-19 infection
title_fullStr Guillain-Barré syndrome associated with COVID-19 infection
title_full_unstemmed Guillain-Barré syndrome associated with COVID-19 infection
title_short Guillain-Barré syndrome associated with COVID-19 infection
title_sort guillain-barré syndrome associated with covid-19 infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687474/
https://www.ncbi.nlm.nih.gov/pubmed/33282073
http://dx.doi.org/10.11604/pamj.supp.2020.35.2.25003
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