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Clinicopathological associations and prognostic values of IDH1 gene mutation, MGMT gene promoter methylation, and PD-L1 expressions in high-grade glioma treated with standard treatment

INTRODUCTION: the objective was to evaluate the impact of IDH1 R132H mutation, MGMT methylation and PD-L1 expression in high grade glioma that received standard therapy (surgery, radiation and chemotherapy) to overall survival (OS). METHODS: this is a retrospective study of 35 high grade glioma case...

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Detalles Bibliográficos
Autores principales: July, Julius, Patricia, Diana, Gunawan, Pricilla Yani, Setiajaya, Handrianto, Ginting, Teridah Ernala, Putra, Teguh Pribadi, Wuisan, Zerlina, Budhiarko, Dini, Masykura, Najmiatul, Prayogi, Gintang, Utomo, Ahmad Rusdan, Tandean, Steven, Loe, Michael Lumintang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687483/
https://www.ncbi.nlm.nih.gov/pubmed/33282092
http://dx.doi.org/10.11604/pamj.2020.36.309.24831