Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report

Severe infection with COVID-19 virus in pregnancy offers unique management challenges for the obstetrician and critical care specialist. We report the case of a woman at 26 weeks of gestation with acute respiratory distress syndrome secondary to COVID-19 infection treated with dexamethasone, remdesi...

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Detalles Bibliográficos
Autores principales: Jacobson, Jennifer, Antony, Kathleen, Beninati, Michael, Alward, William, Hoppe, Kara K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687655/
https://www.ncbi.nlm.nih.gov/pubmed/33262932
http://dx.doi.org/10.1016/j.crwh.2020.e00273
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author Jacobson, Jennifer
Antony, Kathleen
Beninati, Michael
Alward, William
Hoppe, Kara K.
author_facet Jacobson, Jennifer
Antony, Kathleen
Beninati, Michael
Alward, William
Hoppe, Kara K.
author_sort Jacobson, Jennifer
collection PubMed
description Severe infection with COVID-19 virus in pregnancy offers unique management challenges for the obstetrician and critical care specialist. We report the case of a woman at 26 weeks of gestation with acute respiratory distress syndrome secondary to COVID-19 infection treated with dexamethasone, remdesivir, convalescent plasma and mechanical ventilation. Cesarean delivery was performed at 29 weeks due to worsening maternal status. This case offers insight into the assessment and successful use of treatment strategies, including dexamethasone, remdesivir, convalescent plasma, early prone positioning, conservative fluid management, permissive hypoxia and low tidal volume parameters with ventilator support for pregnancies affected by severe COVID-19 infection.
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spelling pubmed-76876552020-11-27 Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report Jacobson, Jennifer Antony, Kathleen Beninati, Michael Alward, William Hoppe, Kara K. Case Rep Womens Health Article Severe infection with COVID-19 virus in pregnancy offers unique management challenges for the obstetrician and critical care specialist. We report the case of a woman at 26 weeks of gestation with acute respiratory distress syndrome secondary to COVID-19 infection treated with dexamethasone, remdesivir, convalescent plasma and mechanical ventilation. Cesarean delivery was performed at 29 weeks due to worsening maternal status. This case offers insight into the assessment and successful use of treatment strategies, including dexamethasone, remdesivir, convalescent plasma, early prone positioning, conservative fluid management, permissive hypoxia and low tidal volume parameters with ventilator support for pregnancies affected by severe COVID-19 infection. Elsevier 2020-11-25 /pmc/articles/PMC7687655/ /pubmed/33262932 http://dx.doi.org/10.1016/j.crwh.2020.e00273 Text en © 2020 The Authors. Published by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Jacobson, Jennifer
Antony, Kathleen
Beninati, Michael
Alward, William
Hoppe, Kara K.
Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report
title Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report
title_full Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report
title_fullStr Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report
title_full_unstemmed Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report
title_short Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report
title_sort use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe covid-19 infection in pregnancy: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687655/
https://www.ncbi.nlm.nih.gov/pubmed/33262932
http://dx.doi.org/10.1016/j.crwh.2020.e00273
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