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Improving biomedical named entity recognition with syntactic information

BACKGROUND: Biomedical named entity recognition (BioNER) is an important task for understanding biomedical texts, which can be challenging due to the lack of large-scale labeled training data and domain knowledge. To address the challenge, in addition to using powerful encoders (e.g., biLSTM and Bio...

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Autores principales: Tian, Yuanhe, Shen, Wang, Song, Yan, Xia, Fei, He, Min, Li, Kenli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687711/
https://www.ncbi.nlm.nih.gov/pubmed/33238875
http://dx.doi.org/10.1186/s12859-020-03834-6
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author Tian, Yuanhe
Shen, Wang
Song, Yan
Xia, Fei
He, Min
Li, Kenli
author_facet Tian, Yuanhe
Shen, Wang
Song, Yan
Xia, Fei
He, Min
Li, Kenli
author_sort Tian, Yuanhe
collection PubMed
description BACKGROUND: Biomedical named entity recognition (BioNER) is an important task for understanding biomedical texts, which can be challenging due to the lack of large-scale labeled training data and domain knowledge. To address the challenge, in addition to using powerful encoders (e.g., biLSTM and BioBERT), one possible method is to leverage extra knowledge that is easy to obtain. Previous studies have shown that auto-processed syntactic information can be a useful resource to improve model performance, but their approaches are limited to directly concatenating the embeddings of syntactic information to the input word embeddings. Therefore, such syntactic information is leveraged in an inflexible way, where inaccurate one may hurt model performance. RESULTS: In this paper, we propose BioKMNER, a BioNER model for biomedical texts with key-value memory networks (KVMN) to incorporate auto-processed syntactic information. We evaluate BioKMNER on six English biomedical datasets, where our method with KVMN outperforms the strong baseline method, namely, BioBERT, from the previous study on all datasets. Specifically, the F1 scores of our best performing model are 85.29% on BC2GM, 77.83% on JNLPBA, 94.22% on BC5CDR-chemical, 90.08% on NCBI-disease, 89.24% on LINNAEUS, and 76.33% on Species-800, where state-of-the-art performance is obtained on four of them (i.e., BC2GM, BC5CDR-chemical, NCBI-disease, and Species-800). CONCLUSION: The experimental results on six English benchmark datasets demonstrate that auto-processed syntactic information can be a useful resource for BioNER and our method with KVMN can appropriately leverage such information to improve model performance.
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spelling pubmed-76877112020-11-30 Improving biomedical named entity recognition with syntactic information Tian, Yuanhe Shen, Wang Song, Yan Xia, Fei He, Min Li, Kenli BMC Bioinformatics Research Article BACKGROUND: Biomedical named entity recognition (BioNER) is an important task for understanding biomedical texts, which can be challenging due to the lack of large-scale labeled training data and domain knowledge. To address the challenge, in addition to using powerful encoders (e.g., biLSTM and BioBERT), one possible method is to leverage extra knowledge that is easy to obtain. Previous studies have shown that auto-processed syntactic information can be a useful resource to improve model performance, but their approaches are limited to directly concatenating the embeddings of syntactic information to the input word embeddings. Therefore, such syntactic information is leveraged in an inflexible way, where inaccurate one may hurt model performance. RESULTS: In this paper, we propose BioKMNER, a BioNER model for biomedical texts with key-value memory networks (KVMN) to incorporate auto-processed syntactic information. We evaluate BioKMNER on six English biomedical datasets, where our method with KVMN outperforms the strong baseline method, namely, BioBERT, from the previous study on all datasets. Specifically, the F1 scores of our best performing model are 85.29% on BC2GM, 77.83% on JNLPBA, 94.22% on BC5CDR-chemical, 90.08% on NCBI-disease, 89.24% on LINNAEUS, and 76.33% on Species-800, where state-of-the-art performance is obtained on four of them (i.e., BC2GM, BC5CDR-chemical, NCBI-disease, and Species-800). CONCLUSION: The experimental results on six English benchmark datasets demonstrate that auto-processed syntactic information can be a useful resource for BioNER and our method with KVMN can appropriately leverage such information to improve model performance. BioMed Central 2020-11-25 /pmc/articles/PMC7687711/ /pubmed/33238875 http://dx.doi.org/10.1186/s12859-020-03834-6 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Tian, Yuanhe
Shen, Wang
Song, Yan
Xia, Fei
He, Min
Li, Kenli
Improving biomedical named entity recognition with syntactic information
title Improving biomedical named entity recognition with syntactic information
title_full Improving biomedical named entity recognition with syntactic information
title_fullStr Improving biomedical named entity recognition with syntactic information
title_full_unstemmed Improving biomedical named entity recognition with syntactic information
title_short Improving biomedical named entity recognition with syntactic information
title_sort improving biomedical named entity recognition with syntactic information
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687711/
https://www.ncbi.nlm.nih.gov/pubmed/33238875
http://dx.doi.org/10.1186/s12859-020-03834-6
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