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Hepatocyte high-mobility group box 1 protects against steatosis and cellular stress during high fat diet feeding

BACKGROUND: Circulating high-mobility group box 1 (HMGB1) plays important roles in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Intracellular HMGB1 is critical for the biology of hepatocytes. However, the intracellular role of HMGB1 in hepatocellular steatosis is unknown. Therefore,...

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Detalles Bibliográficos
Autores principales:	Lin, Minjie, Long, Jungke, Li, Wenbo, Yang, Chenxuan, Loughran, Patricia, O’Doherty, Robert, Billiar, Timothy R., Deng, Meihong, Scott, Melanie J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687718/ https://www.ncbi.nlm.nih.gov/pubmed/33238880 http://dx.doi.org/10.1186/s10020-020-00227-6

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