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Autophagy-mediated metabolic effects of aspirin
Salicylate, the active derivative of aspirin (acetylsalicylate), recapitulates the mode of action of caloric restriction inasmuch as it stimulates autophagy through the inhibition of the acetyltransferase activity of EP300. Here, we directly compared the metabolic effects of aspirin medication with...
Autores principales: | Castoldi, Francesca, Humeau, Juliette, Martins, Isabelle, Lachkar, Sylvie, Loew, Damarys, Dingli, Florent, Durand, Sylvère, Enot, David, Bossut, Noëlie, Chery, Alexis, Aprahamian, Fanny, Demont, Yohann, Opolon, Paule, Signolle, Nicolas, Sauvat, Allan, Semeraro, Michaela, Bezu, Lucillia, Baracco, Elisa Elena, Vacchelli, Erika, Pol, Jonathan G., Lévesque, Sarah, Bloy, Norma, Sica, Valentina, Maiuri, Maria Chiara, Kroemer, Guido, Pietrocola, Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687910/ https://www.ncbi.nlm.nih.gov/pubmed/33298861 http://dx.doi.org/10.1038/s41420-020-00365-0 |
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