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Autophagy-mediated metabolic effects of aspirin

Salicylate, the active derivative of aspirin (acetylsalicylate), recapitulates the mode of action of caloric restriction inasmuch as it stimulates autophagy through the inhibition of the acetyltransferase activity of EP300. Here, we directly compared the metabolic effects of aspirin medication with...

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Detalles Bibliográficos
Autores principales: Castoldi, Francesca, Humeau, Juliette, Martins, Isabelle, Lachkar, Sylvie, Loew, Damarys, Dingli, Florent, Durand, Sylvère, Enot, David, Bossut, Noëlie, Chery, Alexis, Aprahamian, Fanny, Demont, Yohann, Opolon, Paule, Signolle, Nicolas, Sauvat, Allan, Semeraro, Michaela, Bezu, Lucillia, Baracco, Elisa Elena, Vacchelli, Erika, Pol, Jonathan G., Lévesque, Sarah, Bloy, Norma, Sica, Valentina, Maiuri, Maria Chiara, Kroemer, Guido, Pietrocola, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687910/
https://www.ncbi.nlm.nih.gov/pubmed/33298861
http://dx.doi.org/10.1038/s41420-020-00365-0

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