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Population-scale study of eRNA transcription reveals bipartite functional enhancer architecture

Enhancer RNAs (eRNA) are unstable non-coding RNAs, transcribed bidirectionally from active regulatory sequences, whose expression levels correlate with enhancer activity. We use capped-nascent-RNA sequencing to efficiently capture bidirectional transcription initiation across several human lymphobla...

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Detalles Bibliográficos
Autores principales: Kristjánsdóttir, Katla, Dziubek, Alexis, Kang, Hyun Min, Kwak, Hojoong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687912/
https://www.ncbi.nlm.nih.gov/pubmed/33235186
http://dx.doi.org/10.1038/s41467-020-19829-z