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Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis

Adipose-derived stem cells (ASCs) exhibit self-renewal and pluripotency. The differentiation potency of ASCs has been reported to deteriorate with aging; however, relevant studies used ASCs that were isolated and subcultured several times. It is still unclear whether subcultured ASCs accurately refl...

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Detalles Bibliográficos
Autores principales: Doshida, Yuta, Sano, Haruka, Iwabuchi, Sadahiro, Aigaki, Toshiro, Yoshida, Masayuki, Hashimoto, Shinichi, Ishigami, Akihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688117/
https://www.ncbi.nlm.nih.gov/pubmed/33237970
http://dx.doi.org/10.1371/journal.pone.0242171