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Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis
Adipose-derived stem cells (ASCs) exhibit self-renewal and pluripotency. The differentiation potency of ASCs has been reported to deteriorate with aging; however, relevant studies used ASCs that were isolated and subcultured several times. It is still unclear whether subcultured ASCs accurately refl...
Autores principales: | Doshida, Yuta, Sano, Haruka, Iwabuchi, Sadahiro, Aigaki, Toshiro, Yoshida, Masayuki, Hashimoto, Shinichi, Ishigami, Akihito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688117/ https://www.ncbi.nlm.nih.gov/pubmed/33237970 http://dx.doi.org/10.1371/journal.pone.0242171 |
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