Cargando…

COVID-19 IgG/IgM antibody testing in Los Angeles County, California

Evidence suggests that asymptomatic and mild SARS-CoV-2 infections comprise > 95% of all cases. Developing a test that indicates past infection and possible immunity against the virus is important. We administered 244 antibody tests to three groups of high-risk population. The test consisted of a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmad, Khadije, Rezvanizadeh, Vahid, Dahal, Suraj, Kinninger, April, Ghanem, Ahmed K., Lakshmanan, Suvasini, Hamal, Sajad, Flores, Ferdinand, Dailing, Christopher, Roy, Sion K., Budoff, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688294/
https://www.ncbi.nlm.nih.gov/pubmed/33241444
http://dx.doi.org/10.1007/s10096-020-04111-3
_version_ 1783613678650654720
author Ahmad, Khadije
Rezvanizadeh, Vahid
Dahal, Suraj
Kinninger, April
Ghanem, Ahmed K.
Lakshmanan, Suvasini
Hamal, Sajad
Flores, Ferdinand
Dailing, Christopher
Roy, Sion K.
Budoff, Matthew J.
author_facet Ahmad, Khadije
Rezvanizadeh, Vahid
Dahal, Suraj
Kinninger, April
Ghanem, Ahmed K.
Lakshmanan, Suvasini
Hamal, Sajad
Flores, Ferdinand
Dailing, Christopher
Roy, Sion K.
Budoff, Matthew J.
author_sort Ahmad, Khadije
collection PubMed
description Evidence suggests that asymptomatic and mild SARS-CoV-2 infections comprise > 95% of all cases. Developing a test that indicates past infection and possible immunity against the virus is important. We administered 244 antibody tests to three groups of high-risk population. The test consisted of an IgG component and an IgM component. The overall IgM/IgG positivity for patients with none, mild, moderate, and severe symptoms were 21.1%, 21.8%, 14.2%, and 26.9%, respectively. Those with moderate or severe symptoms were no more or less likely to have positive antibody tests than those with no or mild symptoms.
format Online
Article
Text
id pubmed-7688294
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-76882942020-11-27 COVID-19 IgG/IgM antibody testing in Los Angeles County, California Ahmad, Khadije Rezvanizadeh, Vahid Dahal, Suraj Kinninger, April Ghanem, Ahmed K. Lakshmanan, Suvasini Hamal, Sajad Flores, Ferdinand Dailing, Christopher Roy, Sion K. Budoff, Matthew J. Eur J Clin Microbiol Infect Dis Brief Report Evidence suggests that asymptomatic and mild SARS-CoV-2 infections comprise > 95% of all cases. Developing a test that indicates past infection and possible immunity against the virus is important. We administered 244 antibody tests to three groups of high-risk population. The test consisted of an IgG component and an IgM component. The overall IgM/IgG positivity for patients with none, mild, moderate, and severe symptoms were 21.1%, 21.8%, 14.2%, and 26.9%, respectively. Those with moderate or severe symptoms were no more or less likely to have positive antibody tests than those with no or mild symptoms. Springer Berlin Heidelberg 2020-11-25 2021 /pmc/articles/PMC7688294/ /pubmed/33241444 http://dx.doi.org/10.1007/s10096-020-04111-3 Text en © Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Brief Report
Ahmad, Khadije
Rezvanizadeh, Vahid
Dahal, Suraj
Kinninger, April
Ghanem, Ahmed K.
Lakshmanan, Suvasini
Hamal, Sajad
Flores, Ferdinand
Dailing, Christopher
Roy, Sion K.
Budoff, Matthew J.
COVID-19 IgG/IgM antibody testing in Los Angeles County, California
title COVID-19 IgG/IgM antibody testing in Los Angeles County, California
title_full COVID-19 IgG/IgM antibody testing in Los Angeles County, California
title_fullStr COVID-19 IgG/IgM antibody testing in Los Angeles County, California
title_full_unstemmed COVID-19 IgG/IgM antibody testing in Los Angeles County, California
title_short COVID-19 IgG/IgM antibody testing in Los Angeles County, California
title_sort covid-19 igg/igm antibody testing in los angeles county, california
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688294/
https://www.ncbi.nlm.nih.gov/pubmed/33241444
http://dx.doi.org/10.1007/s10096-020-04111-3
work_keys_str_mv AT ahmadkhadije covid19iggigmantibodytestinginlosangelescountycalifornia
AT rezvanizadehvahid covid19iggigmantibodytestinginlosangelescountycalifornia
AT dahalsuraj covid19iggigmantibodytestinginlosangelescountycalifornia
AT kinningerapril covid19iggigmantibodytestinginlosangelescountycalifornia
AT ghanemahmedk covid19iggigmantibodytestinginlosangelescountycalifornia
AT lakshmanansuvasini covid19iggigmantibodytestinginlosangelescountycalifornia
AT hamalsajad covid19iggigmantibodytestinginlosangelescountycalifornia
AT floresferdinand covid19iggigmantibodytestinginlosangelescountycalifornia
AT dailingchristopher covid19iggigmantibodytestinginlosangelescountycalifornia
AT roysionk covid19iggigmantibodytestinginlosangelescountycalifornia
AT budoffmatthewj covid19iggigmantibodytestinginlosangelescountycalifornia