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Condition for Global Stability for a SEIR Model Incorporating Exogenous Reinfection and Primary Infection Mechanisms

A mathematical model incorporating exogenous reinfection and primary progression infection processes is proposed. Global stability is examined using the geometric approach which involves the generalization of Poincare-Bendixson criterion for systems of n-ordinary differential equations. Analytical r...

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Autor principal: Wangari, Isaac Mwangi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688353/
https://www.ncbi.nlm.nih.gov/pubmed/33281923
http://dx.doi.org/10.1155/2020/9435819
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author Wangari, Isaac Mwangi
author_facet Wangari, Isaac Mwangi
author_sort Wangari, Isaac Mwangi
collection PubMed
description A mathematical model incorporating exogenous reinfection and primary progression infection processes is proposed. Global stability is examined using the geometric approach which involves the generalization of Poincare-Bendixson criterion for systems of n-ordinary differential equations. Analytical results show that for a Susceptible-Exposed-Infective-Recovered (SEIR) model incorporating exogenous reinfection and primary progression infection mechanisms, an additional condition is required to fulfill the Bendixson criterion for global stability. That is, the model is globally asymptotically stable whenever a parameter accounting for exogenous reinfection is less than the ratio of background mortality to effective contact rate. Numerical simulations are also presented to support theoretical findings.
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spelling pubmed-76883532020-12-04 Condition for Global Stability for a SEIR Model Incorporating Exogenous Reinfection and Primary Infection Mechanisms Wangari, Isaac Mwangi Comput Math Methods Med Research Article A mathematical model incorporating exogenous reinfection and primary progression infection processes is proposed. Global stability is examined using the geometric approach which involves the generalization of Poincare-Bendixson criterion for systems of n-ordinary differential equations. Analytical results show that for a Susceptible-Exposed-Infective-Recovered (SEIR) model incorporating exogenous reinfection and primary progression infection mechanisms, an additional condition is required to fulfill the Bendixson criterion for global stability. That is, the model is globally asymptotically stable whenever a parameter accounting for exogenous reinfection is less than the ratio of background mortality to effective contact rate. Numerical simulations are also presented to support theoretical findings. Hindawi 2020-11-17 /pmc/articles/PMC7688353/ /pubmed/33281923 http://dx.doi.org/10.1155/2020/9435819 Text en Copyright © 2020 Isaac Mwangi Wangari. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wangari, Isaac Mwangi
Condition for Global Stability for a SEIR Model Incorporating Exogenous Reinfection and Primary Infection Mechanisms
title Condition for Global Stability for a SEIR Model Incorporating Exogenous Reinfection and Primary Infection Mechanisms
title_full Condition for Global Stability for a SEIR Model Incorporating Exogenous Reinfection and Primary Infection Mechanisms
title_fullStr Condition for Global Stability for a SEIR Model Incorporating Exogenous Reinfection and Primary Infection Mechanisms
title_full_unstemmed Condition for Global Stability for a SEIR Model Incorporating Exogenous Reinfection and Primary Infection Mechanisms
title_short Condition for Global Stability for a SEIR Model Incorporating Exogenous Reinfection and Primary Infection Mechanisms
title_sort condition for global stability for a seir model incorporating exogenous reinfection and primary infection mechanisms
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688353/
https://www.ncbi.nlm.nih.gov/pubmed/33281923
http://dx.doi.org/10.1155/2020/9435819
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