Bioequivalence of macitentan and tadalafil given as fixed‐dose combination or single‐component tablets in healthy subjects

AIMS: To demonstrate the bioequivalence of macitentan/tadalafil fixed‐dose combination (FDC) tablets with single‐component tablets of macitentan and tadalafil in healthy subjects. METHODS: Studies AC‐077‐101 and AC‐077‐103 were single‐centre, open‐label, single‐dose, 2‐period, randomized, crossover...

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Detalles Bibliográficos
Autores principales: Grill, Simon, Bruderer, Shirin, Sidharta, Patricia N., Antonova, Mariya, Globig, Susanne, Carlson, James, Schultz, Armin, Csonka, Dénes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688529/
https://www.ncbi.nlm.nih.gov/pubmed/32374030
http://dx.doi.org/10.1111/bcp.14347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688529/
https://www.ncbi.nlm.nih.gov/pubmed/32374030
http://dx.doi.org/10.1111/bcp.14347

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