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The heparan sulfate proteoglycan Syndecan-1 influences local bone cell communication via the RANKL/OPG axis

The heparan sulfate proteoglycan Syndecan-1, a mediator of signals between the extracellular matrix and cells involved is able to interact with OPG, one of the major regulators of osteoclastogenesis. The potential of osteoblasts to induce osteoclastogenesis is characterized by a switch of OPG (low o...

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Detalles Bibliográficos
Autores principales: Timmen, Melanie, Hidding, Heriburg, Götte, Martin, Khassawna, Thaqif El, Kronenberg, Daniel, Stange, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688641/
https://www.ncbi.nlm.nih.gov/pubmed/33239699
http://dx.doi.org/10.1038/s41598-020-77510-3