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The heparan sulfate proteoglycan Syndecan-1 influences local bone cell communication via the RANKL/OPG axis
The heparan sulfate proteoglycan Syndecan-1, a mediator of signals between the extracellular matrix and cells involved is able to interact with OPG, one of the major regulators of osteoclastogenesis. The potential of osteoblasts to induce osteoclastogenesis is characterized by a switch of OPG (low o...
Autores principales: | Timmen, Melanie, Hidding, Heriburg, Götte, Martin, Khassawna, Thaqif El, Kronenberg, Daniel, Stange, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688641/ https://www.ncbi.nlm.nih.gov/pubmed/33239699 http://dx.doi.org/10.1038/s41598-020-77510-3 |
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