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Resveratrol improves motor function in patients with muscular dystrophies: an open-label, single-arm, phase IIa study

Muscular dystrophies (MDs) are inherited disorders characterized by progressive muscle weakness. Previously, we have shown that resveratrol (3,5,4′-trihydroxy-trans-stilbene), an antioxidant and an activator of the protein deacetylase SIRT1, decreases muscular and cardiac oxidative damage and improv...

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Detalles Bibliográficos
Autores principales: Kawamura, Kentaro, Fukumura, Shinobu, Nikaido, Koki, Tachi, Nobutada, Kozuka, Naoki, Seino, Tsugumi, Hatakeyama, Kingya, Mori, Mitsuru, Ito, Yoichi M., Takami, Akiyoshi, Hinotsu, Shiro, Kuno, Atsushi, Kawasaki, Yukihiko, Horio, Yoshiyuki, Tsutsumi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688653/
https://www.ncbi.nlm.nih.gov/pubmed/33239684
http://dx.doi.org/10.1038/s41598-020-77197-6