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Resveratrol improves motor function in patients with muscular dystrophies: an open-label, single-arm, phase IIa study
Muscular dystrophies (MDs) are inherited disorders characterized by progressive muscle weakness. Previously, we have shown that resveratrol (3,5,4′-trihydroxy-trans-stilbene), an antioxidant and an activator of the protein deacetylase SIRT1, decreases muscular and cardiac oxidative damage and improv...
Autores principales: | Kawamura, Kentaro, Fukumura, Shinobu, Nikaido, Koki, Tachi, Nobutada, Kozuka, Naoki, Seino, Tsugumi, Hatakeyama, Kingya, Mori, Mitsuru, Ito, Yoichi M., Takami, Akiyoshi, Hinotsu, Shiro, Kuno, Atsushi, Kawasaki, Yukihiko, Horio, Yoshiyuki, Tsutsumi, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688653/ https://www.ncbi.nlm.nih.gov/pubmed/33239684 http://dx.doi.org/10.1038/s41598-020-77197-6 |
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