Structural Characterization of Non-structural Protein 9 Complexed With Specific Nanobody Pinpoints Two Important Residues Involved in Porcine Reproductive and Respiratory Syndrome Virus Replication

Porcine reproductive and respiratory syndrome (PRRS), caused by PRRS virus (PRRSV), is a widespread viral disease that has led to huge economic losses for the global swine industry. Non-structural protein 9 (Nsp9) of PRRSV possesses essential RNA-dependent RNA polymerase (RdRp) activity for viral RN...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Li, Rui, Qiao, Songlin, Wang, Jiaxi, Liu, Hongliang, Li, Zhijun, Ma, Hongfang, Yang, Lei, Ruan, Haiyu, Weng, Maoyang, Hiscox, Julian A., Stewart, James P., Nan, Yuchen, Zhang, Gaiping, Zhou, En-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688669/
https://www.ncbi.nlm.nih.gov/pubmed/33281776
http://dx.doi.org/10.3389/fmicb.2020.581856

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