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Tau Filament Self-Assembly and Structure: Tau as a Therapeutic Target
Tau plays an important pathological role in a group of neurodegenerative diseases called tauopathies, including Alzheimer's disease, Pick's disease, chronic traumatic encephalopathy and corticobasal degeneration. In each disease, tau self-assembles abnormally to form filaments that deposit...
Autores principales: | Oakley, Sebastian S., Maina, Mahmoud B., Marshall, Karen E., Al-Hilaly, Youssra K., Harrington, Charlie R., Wischik, Claude M., Serpell, Louise C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688747/ https://www.ncbi.nlm.nih.gov/pubmed/33281730 http://dx.doi.org/10.3389/fneur.2020.590754 |
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