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Fusion of a Novel Native Signal Peptide Enhanced the Secretion and Solubility of Bioactive Human Interferon Gamma Glycoproteins in Nicotiana benthamiana Using the Bamboo Mosaic Virus-Based Expression System

Plant viruses may serve as expression vectors for the efficient production of pharmaceutical proteins in plants. However, the downstream processing and post-translational modifications of the target proteins remain the major challenges. We have previously developed an expression system derived from...

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Detalles Bibliográficos
Autores principales: Jiang, Min-Chao, Hu, Chung-Chi, Hsu, Wei-Li, Hsu, Tsui-Ling, Lin, Na-Sheng, Hsu, Yau-Heiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688984/
https://www.ncbi.nlm.nih.gov/pubmed/33281853
http://dx.doi.org/10.3389/fpls.2020.594758