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Fusion of a Novel Native Signal Peptide Enhanced the Secretion and Solubility of Bioactive Human Interferon Gamma Glycoproteins in Nicotiana benthamiana Using the Bamboo Mosaic Virus-Based Expression System
Plant viruses may serve as expression vectors for the efficient production of pharmaceutical proteins in plants. However, the downstream processing and post-translational modifications of the target proteins remain the major challenges. We have previously developed an expression system derived from...
Autores principales: | Jiang, Min-Chao, Hu, Chung-Chi, Hsu, Wei-Li, Hsu, Tsui-Ling, Lin, Na-Sheng, Hsu, Yau-Heiu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688984/ https://www.ncbi.nlm.nih.gov/pubmed/33281853 http://dx.doi.org/10.3389/fpls.2020.594758 |
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