Short-term treatment with dabigatran alters protein expression patterns in a late-stage tau-based Alzheimer's disease mouse model

Proteins that regulate the coagulation cascade, including thrombin, are elevated in the brains of Alzheimer's disease (AD) patients. While studies using amyloid-based AD transgenic mouse models have implicated thrombin as a protein of interest, the role of thrombin in tau-based animal models ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Iannucci, Jaclyn, Johnson, Shelby L., Majchrzak, Mark, Barlock, Benjamin J., Akhlaghi, Fatemeh, Seeram, Navindra P., Sen, Abhik, Grammas, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689047/
https://www.ncbi.nlm.nih.gov/pubmed/33294639
http://dx.doi.org/10.1016/j.bbrep.2020.100862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689047/
https://www.ncbi.nlm.nih.gov/pubmed/33294639
http://dx.doi.org/10.1016/j.bbrep.2020.100862

Ejemplares similares