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Short-term treatment with dabigatran alters protein expression patterns in a late-stage tau-based Alzheimer's disease mouse model
Proteins that regulate the coagulation cascade, including thrombin, are elevated in the brains of Alzheimer's disease (AD) patients. While studies using amyloid-based AD transgenic mouse models have implicated thrombin as a protein of interest, the role of thrombin in tau-based animal models ha...
Autores principales: | Iannucci, Jaclyn, Johnson, Shelby L., Majchrzak, Mark, Barlock, Benjamin J., Akhlaghi, Fatemeh, Seeram, Navindra P., Sen, Abhik, Grammas, Paula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689047/ https://www.ncbi.nlm.nih.gov/pubmed/33294639 http://dx.doi.org/10.1016/j.bbrep.2020.100862 |
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