Cargando…
Polygenic Risk Score for Early Prediction of Sepsis Risk in the Polytrauma Screening Cohort
BACKGROUND: Increasing genetic variants associated with sepsis have been identified by candidate-gene and genome-wide association studies, but single variants conferred minimal alterations in risk prediction. Our aim is to evaluate whether a weighted genetic risk score (wGRS) that aggregates informa...
Autores principales: | Lu, Hongxiang, Wen, Dalin, Sun, Jianhui, Du, Juan, Qiao, Liang, Zhang, Huacai, Zeng, Ling, Zhang, Lianyang, Jiang, Jianxin, Zhang, Anqiang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689156/ https://www.ncbi.nlm.nih.gov/pubmed/33281864 http://dx.doi.org/10.3389/fgene.2020.545564 |
Ejemplares similares
-
A Functional Variant of CXCL16 Is Associated With Predisposition to Sepsis and MODS in Trauma Patients: Genetic Association Studies
por: Sun, Jianhui, et al.
Publicado: (2021) -
Enhancer polymorphism rs10865710 associated with traumatic sepsis is a regulator of PPARG gene expression
por: Lu, Hongxiang, et al.
Publicado: (2019) -
Host genetic variants in sepsis risk: a field synopsis and meta-analysis
por: Lu, Hongxiang, et al.
Publicado: (2019) -
Plasma Vanin-1 as a Novel Biomarker of Sepsis for Trauma Patients: A Prospective Multicenter Cohort Study
por: Lu, Hongxiang, et al.
Publicado: (2021) -
CTGF promotes the repair and regeneration of alveoli after acute lung injury by promoting the proliferation of subpopulation of AEC2s
por: Sun, Jianhui, et al.
Publicado: (2023)