Single-Cell Transcriptome Analysis Dissects the Replicating Process of Pancreatic Beta Cells in Partial Pancreatectomy Model

Heterogeneity of gene expression and rarity of replication hamper molecular analysis of β-cell mass restoration in adult pancreas. Here, we show transcriptional dynamics in β-cell replication process by single-cell RNA sequencing of murine pancreas with or without partial pancreatectomy. We observed...

Descripción completa

Detalles Bibliográficos
Autores principales: Tatsuoka, Hisato, Sakamoto, Satoko, Yabe, Daisuke, Kabai, Ryotaro, Kato, Unyanee, Okumura, Tatsuya, Botagarova, Ainur, Tokumoto, Shinsuke, Usui, Ryota, Ogura, Masahito, Nagashima, Kazuaki, Mukai, Eri, Fujitani, Yoshio, Watanabe, Akira, Inagaki, Nobuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689163/
https://www.ncbi.nlm.nih.gov/pubmed/33294783
http://dx.doi.org/10.1016/j.isci.2020.101774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689163/
https://www.ncbi.nlm.nih.gov/pubmed/33294783
http://dx.doi.org/10.1016/j.isci.2020.101774

Ejemplares similares