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Up-regulation of PKR pathway contributes to L-NAME induced hypertension and renal damage

OBJECTIVE: Hypertension induced kidney damage is often associated with fibrosis and tubular apoptosis. Double-stranded protein kinase (PKR) is a well recognized inducer of inflammation and apoptosis. However, role of PKR in hypertension coupled renal damage is still not explored. Therefore here we s...

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Detalles Bibliográficos
Autores principales: Kalra, Jaspreet, Bhat, Audesh, Jadhav, KirtiKumar B, Dhar, Arti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689172/
https://www.ncbi.nlm.nih.gov/pubmed/33294654
http://dx.doi.org/10.1016/j.heliyon.2020.e05463

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