Cargando…

Tandospirone, a Partial 5-HT(1A) Receptor Agonist, Administered Systemically or Into Anterior Cingulate Attenuates Repetitive Behaviors in Shank3B Mice

BACKGROUND: Several cases of autism spectrum disorder have been linked to mutations in the SHANK3 gene. Haploinsufficiency of the SHANK3 gene contributes to Phelan-McDermid syndrome, which often presents an autism spectrum disorder phenotype along with moderate to severe intellectual disability. A S...

Descripción completa

Detalles Bibliográficos
Autores principales: Dunn, Jeffrey T, Mroczek, Jessica, Patel, Harsh R, Ragozzino, Michael E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689206/
https://www.ncbi.nlm.nih.gov/pubmed/32619232
http://dx.doi.org/10.1093/ijnp/pyaa047