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A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay
A 62‐year‐old woman presented with a dry cough lasting 18 months. She had previously been examined by multiple doctors, but no abnormalities were observed. Several medications such as rabeprazole and inhaled corticosteroids were administered as test treatments without any improvement. Therefore, the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689238/ https://www.ncbi.nlm.nih.gov/pubmed/33304721 http://dx.doi.org/10.1002/jgf2.348 |
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author | Kikuchi, Asuka Kawamoto, Ryuichi Mizumoto, Junki Akase, Taichi Ninomiya, Daisuke Kumagi, Teru |
author_facet | Kikuchi, Asuka Kawamoto, Ryuichi Mizumoto, Junki Akase, Taichi Ninomiya, Daisuke Kumagi, Teru |
author_sort | Kikuchi, Asuka |
collection | PubMed |
description | A 62‐year‐old woman presented with a dry cough lasting 18 months. She had previously been examined by multiple doctors, but no abnormalities were observed. Several medications such as rabeprazole and inhaled corticosteroids were administered as test treatments without any improvement. Therefore, the possibility of biological disease, including acid reflux, had been mistakenly ruled out. We examined the sputum gram stain. The result showed phagocyted normal bacterial flora, suggesting aspiration. Laryngoscopy revealed edema of the arytenoid cartilage. The patient was finally diagnosed with laryngopharyngeal reflux and silent aspiration. This case suggested that the ineffectiveness of proton‐pump inhibitors cannot always exclude the presence of reflux disease and the usefulness of gram stain examination to detect silent aspiration. |
format | Online Article Text |
id | pubmed-7689238 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-76892382020-12-09 A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay Kikuchi, Asuka Kawamoto, Ryuichi Mizumoto, Junki Akase, Taichi Ninomiya, Daisuke Kumagi, Teru J Gen Fam Med Case Reports A 62‐year‐old woman presented with a dry cough lasting 18 months. She had previously been examined by multiple doctors, but no abnormalities were observed. Several medications such as rabeprazole and inhaled corticosteroids were administered as test treatments without any improvement. Therefore, the possibility of biological disease, including acid reflux, had been mistakenly ruled out. We examined the sputum gram stain. The result showed phagocyted normal bacterial flora, suggesting aspiration. Laryngoscopy revealed edema of the arytenoid cartilage. The patient was finally diagnosed with laryngopharyngeal reflux and silent aspiration. This case suggested that the ineffectiveness of proton‐pump inhibitors cannot always exclude the presence of reflux disease and the usefulness of gram stain examination to detect silent aspiration. John Wiley and Sons Inc. 2020-07-18 /pmc/articles/PMC7689238/ /pubmed/33304721 http://dx.doi.org/10.1002/jgf2.348 Text en © 2020 The Authors. Journal of General and Family Medicine published by John Wiley & Sons Australia, Ltd on behalf of Japan Primary Care Association This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Kikuchi, Asuka Kawamoto, Ryuichi Mizumoto, Junki Akase, Taichi Ninomiya, Daisuke Kumagi, Teru A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay |
title | A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay |
title_full | A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay |
title_fullStr | A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay |
title_full_unstemmed | A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay |
title_short | A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay |
title_sort | case of laryngopharyngeal reflux‐associated chronic cough: misinterpretation of treatment efficacy causes diagnostic delay |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689238/ https://www.ncbi.nlm.nih.gov/pubmed/33304721 http://dx.doi.org/10.1002/jgf2.348 |
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