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A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay

A 62‐year‐old woman presented with a dry cough lasting 18 months. She had previously been examined by multiple doctors, but no abnormalities were observed. Several medications such as rabeprazole and inhaled corticosteroids were administered as test treatments without any improvement. Therefore, the...

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Autores principales: Kikuchi, Asuka, Kawamoto, Ryuichi, Mizumoto, Junki, Akase, Taichi, Ninomiya, Daisuke, Kumagi, Teru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689238/
https://www.ncbi.nlm.nih.gov/pubmed/33304721
http://dx.doi.org/10.1002/jgf2.348
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author Kikuchi, Asuka
Kawamoto, Ryuichi
Mizumoto, Junki
Akase, Taichi
Ninomiya, Daisuke
Kumagi, Teru
author_facet Kikuchi, Asuka
Kawamoto, Ryuichi
Mizumoto, Junki
Akase, Taichi
Ninomiya, Daisuke
Kumagi, Teru
author_sort Kikuchi, Asuka
collection PubMed
description A 62‐year‐old woman presented with a dry cough lasting 18 months. She had previously been examined by multiple doctors, but no abnormalities were observed. Several medications such as rabeprazole and inhaled corticosteroids were administered as test treatments without any improvement. Therefore, the possibility of biological disease, including acid reflux, had been mistakenly ruled out. We examined the sputum gram stain. The result showed phagocyted normal bacterial flora, suggesting aspiration. Laryngoscopy revealed edema of the arytenoid cartilage. The patient was finally diagnosed with laryngopharyngeal reflux and silent aspiration. This case suggested that the ineffectiveness of proton‐pump inhibitors cannot always exclude the presence of reflux disease and the usefulness of gram stain examination to detect silent aspiration.
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spelling pubmed-76892382020-12-09 A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay Kikuchi, Asuka Kawamoto, Ryuichi Mizumoto, Junki Akase, Taichi Ninomiya, Daisuke Kumagi, Teru J Gen Fam Med Case Reports A 62‐year‐old woman presented with a dry cough lasting 18 months. She had previously been examined by multiple doctors, but no abnormalities were observed. Several medications such as rabeprazole and inhaled corticosteroids were administered as test treatments without any improvement. Therefore, the possibility of biological disease, including acid reflux, had been mistakenly ruled out. We examined the sputum gram stain. The result showed phagocyted normal bacterial flora, suggesting aspiration. Laryngoscopy revealed edema of the arytenoid cartilage. The patient was finally diagnosed with laryngopharyngeal reflux and silent aspiration. This case suggested that the ineffectiveness of proton‐pump inhibitors cannot always exclude the presence of reflux disease and the usefulness of gram stain examination to detect silent aspiration. John Wiley and Sons Inc. 2020-07-18 /pmc/articles/PMC7689238/ /pubmed/33304721 http://dx.doi.org/10.1002/jgf2.348 Text en © 2020 The Authors. Journal of General and Family Medicine published by John Wiley & Sons Australia, Ltd on behalf of Japan Primary Care Association This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Kikuchi, Asuka
Kawamoto, Ryuichi
Mizumoto, Junki
Akase, Taichi
Ninomiya, Daisuke
Kumagi, Teru
A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay
title A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay
title_full A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay
title_fullStr A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay
title_full_unstemmed A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay
title_short A case of laryngopharyngeal reflux‐associated chronic cough: Misinterpretation of treatment efficacy causes diagnostic delay
title_sort case of laryngopharyngeal reflux‐associated chronic cough: misinterpretation of treatment efficacy causes diagnostic delay
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689238/
https://www.ncbi.nlm.nih.gov/pubmed/33304721
http://dx.doi.org/10.1002/jgf2.348
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