Synthetic Peptide Libraries Designed From a Minimal Alpha-Helical Domain of AS-48-Bacteriocin Homologs Exhibit Potent Antibacterial Activity

The circularized bacteriocin enterocin AS-48 produced by Enterococcus sp. exhibits antibacterial activity through membrane disruption. The membrane-penetrating activity of enterocin AS-48 has been attributed to a specific alpha-helical region on the circular peptide. Truncated, linearized forms cont...

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Detalles Bibliográficos
Autores principales: Ross, Jessica N., Fields, Francisco R., Kalwajtys, Veronica R., Gonzalez, Alejandro J., O’Connor, Samantha, Zhang, Angela, Moran, Thomas E., Hammers, Daniel E., Carothers, Katelyn E., Lee, Shaun W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689250/
https://www.ncbi.nlm.nih.gov/pubmed/33281785
http://dx.doi.org/10.3389/fmicb.2020.589666

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