Immunogenicity of a single-dose compared with a two-dose primary series followed by a booster dose of ten-valent or 13-valent pneumococcal conjugate vaccine in South African children: an open-label, randomised, non-inferiority trial

BACKGROUND: Routine childhood immunisation with pneumococcal conjugate vaccine (PCV) has changed the epidemiology of pneumococcal disease across age groups, providing an opportunity to reconsider PCV dosing schedules. We aimed to evaluate the post-booster dose immunogenicity of ten-valent (PCV10) an...

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Detalles Bibliográficos
Autores principales: Madhi, Shabir A, Mutsaerts, Eleonora AML, Izu, Alane, Boyce, Welekazi, Bhikha, Sutika, Ikulinda, Benit T, Jose, Lisa, Koen, Anthonet, Nana, Amit J, Moultrie, Andrew, Roalfe, Lucy, Hunt, Adam, Goldblatt, David, Cutland, Clare L, Dorfman, Jeffrey R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science ;, The Lancet Pub. Group 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689288/
https://www.ncbi.nlm.nih.gov/pubmed/32857992
http://dx.doi.org/10.1016/S1473-3099(20)30289-9

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