Drug Screening and Drug Repositioning as Promising Therapeutic Approaches for Spinal Muscular Atrophy Treatment

Spinal muscular atrophy (SMA) is the most common genetic disease affecting infants and young adults. Due to mutation/deletion of the survival motor neuron (SMN) gene, SMA is characterized by the SMN protein lack, resulting in motor neuron impairment, skeletal muscle atrophy and premature death. Even...

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Detalles Bibliográficos
Autores principales: Menduti, Giovanna, Rasà, Daniela Maria, Stanga, Serena, Boido, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689316/
https://www.ncbi.nlm.nih.gov/pubmed/33281605
http://dx.doi.org/10.3389/fphar.2020.592234

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