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Endogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines
Many tumour cells express on their surface proteins of endogenous retroviruses (ERVs) and there are suggestions to use these retroviral antigens as target for anti-tumour vaccines. However, until now there is no convincing data showing that this strategy works, in contrast, there are considerations...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Neoplasia Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689320/ https://www.ncbi.nlm.nih.gov/pubmed/33221683 http://dx.doi.org/10.1016/j.tranon.2020.100941 |
| _version_ | 1783613841330929664 |
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| author | Denner, Joachim |
| author_facet | Denner, Joachim |
| author_sort | Denner, Joachim |
| collection | PubMed |
| description | Many tumour cells express on their surface proteins of endogenous retroviruses (ERVs) and there are suggestions to use these retroviral antigens as target for anti-tumour vaccines. However, until now there is no convincing data showing that this strategy works, in contrast, there are considerations suggesting that this strategy may be harmful if applied. |
| format | Online Article Text |
| id | pubmed-7689320 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Neoplasia Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-76893202020-12-09 Endogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines Denner, Joachim Transl Oncol Short communication Many tumour cells express on their surface proteins of endogenous retroviruses (ERVs) and there are suggestions to use these retroviral antigens as target for anti-tumour vaccines. However, until now there is no convincing data showing that this strategy works, in contrast, there are considerations suggesting that this strategy may be harmful if applied. Neoplasia Press 2020-11-19 /pmc/articles/PMC7689320/ /pubmed/33221683 http://dx.doi.org/10.1016/j.tranon.2020.100941 Text en © 2020 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Short communication Denner, Joachim Endogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines |
| title | Endogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines |
| title_full | Endogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines |
| title_fullStr | Endogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines |
| title_full_unstemmed | Endogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines |
| title_short | Endogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines |
| title_sort | endogenous retroviruses expressed in human tumours cannot be used as targets for anti-tumour vaccines |
| topic | Short communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689320/ https://www.ncbi.nlm.nih.gov/pubmed/33221683 http://dx.doi.org/10.1016/j.tranon.2020.100941 |
| work_keys_str_mv | AT dennerjoachim endogenousretrovirusesexpressedinhumantumourscannotbeusedastargetsforantitumourvaccines |