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Lipopolysaccharide directly inhibits bicarbonate absorption by the renal outer medullary collecting duct

Acidosis is associated with E. coli induced pyelonephritis but whether bacterial cell wall constituents inhibit HCO(3) transport in the outer medullary collecting duct from the inner stripe (OMCDi) is not known. We examined the effect of lipopolysaccharide (LPS), on HCO(3) absorption in isolated per...

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Detalles Bibliográficos
Autores principales: Tsuruoka, Shuichi, Purkerson, Jeffrey M., Schwartz, George J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689453/
https://www.ncbi.nlm.nih.gov/pubmed/33239624
http://dx.doi.org/10.1038/s41598-020-77363-w