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Wisp1 is a circulating factor that stimulates proliferation of adult mouse and human beta cells
Expanding the mass of pancreatic insulin-producing beta cells through re-activation of beta cell replication has been proposed as a therapy to prevent or delay the appearance of diabetes. Pancreatic beta cells exhibit an age-dependent decrease in their proliferative activity, partly related to chang...
Autores principales: | Fernandez-Ruiz, Rebeca, García-Alamán, Ainhoa, Esteban, Yaiza, Mir-Coll, Joan, Serra-Navarro, Berta, Fontcuberta-PiSunyer, Marta, Broca, Christophe, Armanet, Mathieu, Wojtusciszyn, Anne, Kram, Vardit, Young, Marian F., Vidal, Josep, Gomis, Ramon, Gasa, Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689468/ https://www.ncbi.nlm.nih.gov/pubmed/33239617 http://dx.doi.org/10.1038/s41467-020-19657-1 |
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