Cargando…

CircCNTNAP3-TP53-positive feedback loop suppresses malignant progression of esophageal squamous cell carcinoma

Mutation or downregulation of p53 (encoded by TP53) accelerates tumorigenesis and malignant progression in esophageal squamous cell carcinoma (ESCC). However, it is still unknown whether circular RNAs (circRNAs), a novel class of endogenous noncoding RNAs, participate in the regulation of this progr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Hui, Song, Xuming, Wang, Yajing, Yin, Xuewen, Liang, Yingkuan, Zhang, Te, Xu, Lin, Jiang, Feng, Dong, Gaochao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689480/ https://www.ncbi.nlm.nih.gov/pubmed/33239613 http://dx.doi.org/10.1038/s41419-020-03217-y

Ejemplares similares

CircIMMP2L promotes esophageal squamous cell carcinoma malignant progression via CtBP1 nuclear retention dependent epigenetic modification
por: Liang, Yingkuan, et al.
Publicado: (2021)

circDCUN1D4 suppresses tumor metastasis and glycolysis in lung adenocarcinoma by stabilizing TXNIP expression
por: Liang, Yingkuan, et al.
Publicado: (2020)

Tertiary lymphoid structures favor outcome in resected esophageal squamous cell carcinoma
por: Li, Rutao, et al.
Publicado: (2022)

Clinical and prognostic implications of an immune‐related risk model based on TP53 status in lung adenocarcinoma
por: Song, Xuming, et al.
Publicado: (2021)

The High Expression of p53 Is Predictive of Poor Survival Rather TP53 Mutation in Esophageal Squamous Cell Carcinoma
por: Jin, Yan, et al.
Publicado: (2023)

A negative feedback regulatory loop between miR-138 and TP53 is mediated by USP10
por: Luo, Zhenghua, et al.
Publicado: (2019)

Circular RNA has_circ_0067934 is upregulated in esophageal squamous cell carcinoma and promoted proliferation
por: Xia, Wenjia, et al.
Publicado: (2016)

Regulatory feedback loop between TP73 and TRIM32
por: Gonzalez-Cano, L, et al.
Publicado: (2013)

Alterations of the TP53 Gene in Gastric and Esophageal Carcinogenesis
por: Bellini, Marilanda Ferreira, et al.
Publicado: (2012)

N (6)‐methyladenosine‐modified circFUT8 competitively interacts with YTHDF2 and miR‐186‐5p to stabilize FUT8 mRNA to promote malignant progression in lung adenocarcinoma
por: Dong, Gaochao, et al.
Publicado: (2023)

Extremely High Tp53 Mutation Load in Esophageal Squamous Cell Carcinoma in Golestan Province, Iran
por: Abedi-Ardekani, Behnoush, et al.
Publicado: (2011)

A novel gene expression signature-based on B-cell proportion to predict prognosis of patients with lung adenocarcinoma
por: Zhang, Yi, et al.
Publicado: (2021)

PRIMA‐1 induces p53‐mediated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation
por: Furukawa, Haruna, et al.
Publicado: (2017)

Genomic Characterization of TP53–Wild-Type Esophageal Carcinoma()
por: Quaas, Alexander, et al.
Publicado: (2018)

Investigation on the Potential Correlation Between TP53 and Esophageal Cancer
por: Yao, Lihua, et al.
Publicado: (2021)

miR612 is associated with esophageal squamous cell carcinoma development and metastasis, mediated through TP53
por: Zhou, Ping, et al.
Publicado: (2017)

Mutant TP53 G245C and R273H promote cellular malignancy in esophageal squamous cell carcinoma
por: Kang, Nan, et al.
Publicado: (2018)

Analysis of Tp53 Codon 72 Polymorphisms, Tp53 Mutations, and HPV Infection in Cutaneous Squamous Cell Carcinomas
por: Loeb, Keith R., et al.
Publicado: (2012)

Upregulated Collagen COL10A1 Remodels the Extracellular Matrix and Promotes Malignant Progression in Lung Adenocarcinoma
por: Liang, Yingkuan, et al.
Publicado: (2020)

TP53 and TP53-associated genes are correlated with the prognosis of paediatric neuroblastoma
por: Wang, Haiwei, et al.
Publicado: (2022)

Self-restricted circular RNA circSOX2 suppressed the malignant progression in SOX2-amplified LUSC
por: Liang, Yingkuan, et al.
Publicado: (2022)

Tobacco exposure primes the secretion of CCL21 positively associated with tertiary lymphoid structure and response to immunotherapy
por: Yin, Xuewen, et al.
Publicado: (2023)

Association between TP53 gene deletion and protein expression in esophageal squamous cell carcinoma and its prognostic significance
por: Niyaz, Madiniyet, et al.
Publicado: (2020)

Non-disruptive mutation in TP53 DNA-binding domain is a beneficial factor of esophageal squamous cell carcinoma
por: Huang, Minran, et al.
Publicado: (2020)

Porcine model elucidates function of p53 isoform in carcinogenesis and reveals novel circTP53 RNA
por: Niu, Guanglin, et al.
Publicado: (2021)

Early TP53 Alterations Shape Gastric and Esophageal Cancer Development
por: Sahgal, Pranshu, et al.
Publicado: (2021)

Non-genetic stratification reveals epigenetic heterogeneity and identifies vulnerabilities of glycolysis addiction in lung adenocarcinoma subtype
por: Song, Xuming, et al.
Publicado: (2022)

Mitigating the Risk of t-MNs Development: TP53 or Not TP53?
por: Tesio, Melania
Publicado: (2023)

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis
por: Leroy, Bernard, et al.
Publicado: (2013)

Differential impacts of Cntnap2 heterozygosity and Cntnap2 null homozygosity on axon and myelinated fiber development in mouse
por: Cifuentes-Diaz, Carmen, et al.
Publicado: (2023)

circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop
por: Yan, Junyu, et al.
Publicado: (2021)

The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma
por: Omura, Go, et al.
Publicado: (2017)

Association of TP53 codon 72 genotype polymorphism and environmental factors with esophageal squamous cell carcinoma in the Mongolian population of the Chinese region of Inner Mongolia
por: Li, Ming, et al.
Publicado: (2017)

Mutations of CNTNAP1 led to defects in neuronal development
por: Li, Wanxing, et al.
Publicado: (2020)

Defining the Contribution of CNTNAP2 to Autism Susceptibility
por: Sampath, Srirangan, et al.
Publicado: (2013)

Circular RNA circCRIM1 inhibits invasion and metastasis in lung adenocarcinoma through the microRNA (miR)‐182/miR‐93‐leukemia inhibitory factor receptor pathway
por: Wang, Lin, et al.
Publicado: (2019)

Degraded tactile coding in the Cntnap2 mouse model of autism
por: Wang, Han Chin, et al.
Publicado: (2023)

Circ-DLG1 promotes the proliferation of esophageal squamous cell carcinoma
por: Rong, Jun, et al.
Publicado: (2018)

TP53 inhibitor PFTα increases the sensitivity of arsenic trioxide in TP53 wildtype tumor cells
por: Wang, Haiwei, et al.
Publicado: (2022)

MTA2 promotes the metastasis of esophageal squamous cell carcinoma via EIF4E‐Twist feedback loop
por: Dai, Su‐Li, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_p4go56s46q7dhu3hvqucn9mu4p