Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting

Targeting a specific chemokine/receptor axis in atherosclerosis remains challenging. Soluble receptor-based strategies are not established for chemokine receptors due to their discontinuous architecture. Macrophage migration-inhibitory factor (MIF) is an atypical chemokine that promotes atherosclero...

Descripción completa

Detalles Bibliográficos
Autores principales: Kontos, Christos, El Bounkari, Omar, Krammer, Christine, Sinitski, Dzmitry, Hille, Kathleen, Zan, Chunfang, Yan, Guangyao, Wang, Sijia, Gao, Ying, Brandhofer, Markus, Megens, Remco T. A., Hoffmann, Adrian, Pauli, Jessica, Asare, Yaw, Gerra, Simona, Bourilhon, Priscila, Leng, Lin, Eckstein, Hans-Henning, Kempf, Wolfgang E., Pelisek, Jaroslav, Gokce, Ozgun, Maegdefessel, Lars, Bucala, Richard, Dichgans, Martin, Weber, Christian, Kapurniotu, Aphrodite, Bernhagen, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689490/
https://www.ncbi.nlm.nih.gov/pubmed/33239628
http://dx.doi.org/10.1038/s41467-020-19764-z

Ejemplares similares

Ejemplares similares