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Preclinical platform for long-term evaluation of immuno-oncology drugs using hCD34+ humanized mouse model

BACKGROUND: Well-characterized preclinical models are essential for immune-oncology research. We investigated the feasibility of our humanized mouse model for evaluating the long-term efficacy of immunotherapy and biomarkers. METHODS: Humanized mice were generated by injecting human fetal cord blood...

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Detalles Bibliográficos
Autores principales:	Park, Nahee, Pandey, Kamal, Chang, Sei Kyung, Kwon, Ah-Young, Cho, Young Bin, Hur, Jin, Katwal, Nar Bahadur, Kim, Seung Ki, Lee, Seung Ah, Son, Gun Woo, Jo, Jong Min, Ahn, Hee Jung, Moon, Yong Wha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689593/ https://www.ncbi.nlm.nih.gov/pubmed/33239416 http://dx.doi.org/10.1136/jitc-2020-001513

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