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Dual and mutual interaction between microbiota and viral infections: a possible treat for COVID-19
All of humans and other mammalian species are colonized by some types of microorganisms such as bacteria, archaea, unicellular eukaryotes like fungi and protozoa, multicellular eukaryotes like helminths, and viruses, which in whole are called microbiota. These microorganisms have multiple different...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689646/ https://www.ncbi.nlm.nih.gov/pubmed/33243230 http://dx.doi.org/10.1186/s12934-020-01483-1 |
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author | Baghbani, Taha Nikzad, Hossein Azadbakht, Javid Izadpanah, Fatemeh Haddad Kashani, Hamed |
author_facet | Baghbani, Taha Nikzad, Hossein Azadbakht, Javid Izadpanah, Fatemeh Haddad Kashani, Hamed |
author_sort | Baghbani, Taha |
collection | PubMed |
description | All of humans and other mammalian species are colonized by some types of microorganisms such as bacteria, archaea, unicellular eukaryotes like fungi and protozoa, multicellular eukaryotes like helminths, and viruses, which in whole are called microbiota. These microorganisms have multiple different types of interaction with each other. A plethora of evidence suggests that they can regulate immune and digestive systems and also play roles in various diseases, such as mental, cardiovascular, metabolic and some skin diseases. In addition, they take-part in some current health problems like diabetes mellitus, obesity, cancers and infections. Viral infection is one of the most common and problematic health care issues, particularly in recent years that pandemics like SARS and COVID-19 caused a lot of financial and physical damage to the world. There are plenty of articles investigating the interaction between microbiota and infectious diseases. We focused on stimulatory to suppressive effects of microbiota on viral infections, hoping to find a solution to overcome this current pandemic. Then we reviewed mechanistically the effects of both microbiota and probiotics on most of the viruses. But unlike previous studies which concentrated on intestinal microbiota and infection, our focus is on respiratory system’s microbiota and respiratory viral infection, bearing in mind that respiratory system is a proper entry site and residence for viruses, and whereby infection, can lead to asymptomatic, mild, self-limiting, severe or even fatal infection. Finally, we overgeneralize the effects of microbiota on COVID-19 infection. In addition, we reviewed the articles about effects of the microbiota on coronaviruses and suggest some new therapeutic measures. |
format | Online Article Text |
id | pubmed-7689646 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-76896462020-11-27 Dual and mutual interaction between microbiota and viral infections: a possible treat for COVID-19 Baghbani, Taha Nikzad, Hossein Azadbakht, Javid Izadpanah, Fatemeh Haddad Kashani, Hamed Microb Cell Fact Review All of humans and other mammalian species are colonized by some types of microorganisms such as bacteria, archaea, unicellular eukaryotes like fungi and protozoa, multicellular eukaryotes like helminths, and viruses, which in whole are called microbiota. These microorganisms have multiple different types of interaction with each other. A plethora of evidence suggests that they can regulate immune and digestive systems and also play roles in various diseases, such as mental, cardiovascular, metabolic and some skin diseases. In addition, they take-part in some current health problems like diabetes mellitus, obesity, cancers and infections. Viral infection is one of the most common and problematic health care issues, particularly in recent years that pandemics like SARS and COVID-19 caused a lot of financial and physical damage to the world. There are plenty of articles investigating the interaction between microbiota and infectious diseases. We focused on stimulatory to suppressive effects of microbiota on viral infections, hoping to find a solution to overcome this current pandemic. Then we reviewed mechanistically the effects of both microbiota and probiotics on most of the viruses. But unlike previous studies which concentrated on intestinal microbiota and infection, our focus is on respiratory system’s microbiota and respiratory viral infection, bearing in mind that respiratory system is a proper entry site and residence for viruses, and whereby infection, can lead to asymptomatic, mild, self-limiting, severe or even fatal infection. Finally, we overgeneralize the effects of microbiota on COVID-19 infection. In addition, we reviewed the articles about effects of the microbiota on coronaviruses and suggest some new therapeutic measures. BioMed Central 2020-11-26 /pmc/articles/PMC7689646/ /pubmed/33243230 http://dx.doi.org/10.1186/s12934-020-01483-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Review Baghbani, Taha Nikzad, Hossein Azadbakht, Javid Izadpanah, Fatemeh Haddad Kashani, Hamed Dual and mutual interaction between microbiota and viral infections: a possible treat for COVID-19 |
title | Dual and mutual interaction between microbiota and viral infections: a possible treat for COVID-19 |
title_full | Dual and mutual interaction between microbiota and viral infections: a possible treat for COVID-19 |
title_fullStr | Dual and mutual interaction between microbiota and viral infections: a possible treat for COVID-19 |
title_full_unstemmed | Dual and mutual interaction between microbiota and viral infections: a possible treat for COVID-19 |
title_short | Dual and mutual interaction between microbiota and viral infections: a possible treat for COVID-19 |
title_sort | dual and mutual interaction between microbiota and viral infections: a possible treat for covid-19 |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689646/ https://www.ncbi.nlm.nih.gov/pubmed/33243230 http://dx.doi.org/10.1186/s12934-020-01483-1 |
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