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The requirement for cobalt in vitamin B(12): A paradigm for protein metalation()

Vitamin B(12), cobalamin, is a cobalt-containing ring-contracted modified tetrapyrrole that represents one of the most complex small molecules made by nature. In prokaryotes it is utilised as a cofactor, coenzyme, light sensor and gene regulator yet has a restricted role in assisting only two enzyme...

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Detalles Bibliográficos
Autores principales: Osman, Deenah, Cooke, Anastasia, Young, Tessa R., Deery, Evelyne, Robinson, Nigel J., Warren, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689651/
https://www.ncbi.nlm.nih.gov/pubmed/33096143
http://dx.doi.org/10.1016/j.bbamcr.2020.118896