Cargando…

Eosin Y-Catalyzed Synthesis of 3-Aminoimidazo[1,2-a]Pyridines via the HAT Process under Visible Light through Formation of the C–N Bond

[Image: see text] A comfortable, environment-friendly, and metal-free approach for synthesizing the biologically important moiety aminoimidazopyridine through the multicomponent reaction of benzylamine, 2-aminopyridine, and t-butyl isocyanide under visible light using eosin Y as a photocatalyst has...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Himanshu Kumar, Kamal, Arsala, Kumari, Savita, Kumar, Dhirendra, Maury, Suresh Kumar, Srivastava, Vandana, Singh, Sundaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689671/
https://www.ncbi.nlm.nih.gov/pubmed/33251420
http://dx.doi.org/10.1021/acsomega.0c03941
Descripción
Sumario:[Image: see text] A comfortable, environment-friendly, and metal-free approach for synthesizing the biologically important moiety aminoimidazopyridine through the multicomponent reaction of benzylamine, 2-aminopyridine, and t-butyl isocyanide under visible light using eosin Y as a photocatalyst has been developed. Inexpensive, nontoxic, the effortless accessibility of starting materials, and nonparticipation of particular glassware and a photoreactor system are important qualities of the current approach. Strangely, the mild conditions, environment-friendly, and enumerating tolerance of an extensive range of both electron-donating and electron-withdrawing groups are additional features of the approach.