Somatic Deletion in Exon 10 of Aryl Hydrocarbon Receptor Gene in Human GH-Secreting Pituitary Tumors

OBJECTIVE/PURPOSE: The aryl hydrocarbon receptor (AHR) pathway plays a critical role in the biology of Growth Hormone (GH)-secreting pituitary tumor (somatotropinoma). Germline rs2066853 AHR variant was found to be more frequent among acromegaly patients and associated with a more severe disease wit...

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Detalles Bibliográficos
Autores principales: Re, Agnese, Ferraù, Francesco, Cafiero, Concetta, Spagnolo, Federica, Barresi, Valeria, Romeo, Daniela Petronilla, Ragonese, Marta, Grassi, Claudio, Pontecorvi, Alfredo, Farsetti, Antonella, Cannavò, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689685/
https://www.ncbi.nlm.nih.gov/pubmed/33281746
http://dx.doi.org/10.3389/fendo.2020.591039

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